Hydroxyethylamine

Names

[ Name ]:
Hydroxyethylamine

Biological Activity

[Description]:

Hydroxyethylamine (Compd VII) is a SARS-CoV-2 3CLpro inhibitor with an IC50 of ~10 μM in the spread assay. Hydroxyethylamine has potent antiviral activities[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

IC50: ~10 μM (SARS-CoV-2 3CLpro)[1]

[References]

[1]. Yash Gupta, et al. Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach. Bioorg Med Chem. 2021 Oct 1;47:116393.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₄₁N₃O₃

[ Molecular Weight ]:
431.61

Related Compounds

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