TNIK-IN-7

Names

[ Name ]:
TNIK-IN-7

[Synonym ]:
4-methoxy-3-[2-[4-(4-morpholinyl)anilino]-4-pyridinyl]benzonitrile

Biological Activity

[Description]:

TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

11 nM (TNIK)[1]

[References]

[1]. Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂N₄O₂

[ Molecular Weight ]:
386.4

Related Compounds

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