Ivangustin

Names

[ CAS No. ]:
14164-59-1

[ Name ]:
Ivangustin

[Synonym ]:
IVANGUSTIN

Biological Activity

[Description]:

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Ivangustin is against HeLa, PC-3, Hep-2, HepG2, CHO and HUVEC cells with IC50 of 3.2 μM, 4.5 μM, 3.3 μM, 5.2 μM, 6.4 μM, and 9.2 μM, respectively in a SRB colorimetric assay[1].

[References]

[1]. Jiang-Jiang Tang, et al. Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents.Sci Rep. 2018 Jan 29;8(1):1722.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
438.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₀O₃

[ Molecular Weight ]:
248.318

[ Flash Point ]:
187.9±21.5 °C

[ Exact Mass ]:
248.141251

[ LogP ]:
2.11

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.552

Related Compounds

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