GP17

GP17 is a type II kinase inhibitor of the IRE1α endoribonuclease that acts by targeting the ATP-binding pocket of IRE1α.

1. Mehla J, Dedrick RM, Caufield JH, Wagemans J, Sakhawalkar N, Johnson A, Hatfull GF, Uetz P. Virus-host protein-protein interactions of mycobacteriophage Giles. Sci Rep. 2017 Nov 28;7(1):16514. doi: 10.1038/s41598-017-16303-7. PubMed PMID: 29184079; PubMed Central PMCID: PMC5705681.