(rel)-AR234960

Names

[ Name ]:
(rel)-AR234960

Biological Activity

[Description]:

(rel)-AR234960 is an active relative configuration of AR234960. AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac fibroblasts[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> MAPK/ERK Pathway >> ERK

Signaling Pathways >> Stem Cell/Wnt >> ERK

[References]

[1]. Chatterjee A, et al. Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts. PLoS One. 2017 Dec 29;12(12):e0190217.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₀FN₅O₅S

[ Molecular Weight ]:
555.62

Related Compounds

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