Glaucocalyxin D

Names

[ Name ]:
Glaucocalyxin D

Biological Activity

[Description]:

Glaucocalyxin D is a ent-kauranoid-type diterpenoid that can be isolated from Rabdosia japonica. Glaucocalyxin D shows cytotoxicity against various human tumor cell lines. Glaucocalyxin D can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Glaucocalyxin D (0-100 μM；48 h) 对人肿瘤细胞系 A549，CCRF-CEM，HCT116 和 HL-60 具有强烈的细胞毒性。 Cell Cytotoxicity Assay[1] Cell Line: A549, CCRF-CEM, HCT116 and HL-60 cell lines Concentration: 0-100 μM Incubation Time: 48 hours Result: Showed cytotoxicity against A549, HCT116, CCRF-CEM and HL-60 cells with IC50 values of 7.7, 6.04, 2.70 and 3 μM, respectively.

[References]

[1]. Liu HC, et al. Monomeric and dimeric ent-kauranoid-type diterpenoids from rabdosia japonica and their cytotoxicity and anti-HBV activities. Fitoterapia. 2017 Apr;118:94-100.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₀O₅

[ Molecular Weight ]:
374.47100

[ Exact Mass ]:
374.20900

[ PSA ]:
80.67000

[ LogP ]:
2.84580

Related Compounds

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