4′-Chloroacetoacetanilide
Names
[ CAS No. ]:
140-49-8
[ Name ]:
4′-Chloroacetoacetanilide
[Synonym ]:
1-Acetamido-4-chloroacetylbenzene
GR DMV1V1
N-(4-Chlorphenyl)-3-oxobutanamide
N-(4-Chlorophenyl)acetoacetamide
4-acetaminophenacyl chloride
Acetoacetanilide, 4'-chloro-
EINECS 205-416-8
Butanamide, N-(4-chlorophenyl)-3-oxo-
N-[4-(2-chloroacetyl)phenyl]acetamide
MFCD00040869
p-chloroacetylacetanilide
p-Acetamidophenacyl chloride
4-acetylaminophenacyl chloride
Acetoacetanilide, p-chloro-
N-(4-Chlorophenyl)-3-oxobutanamide
4′-Chloroacetoacetanilide
4'-Chloroacetoacetanilide
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
400.5±30.0 °C at 760 mmHg
[ Melting Point ]:
216-219 °C(lit.)
[ Molecular Formula ]:
C10H10ClNO2
[ Molecular Weight ]:
211.645
[ Flash Point ]:
196.0±24.6 °C
[ Exact Mass ]:
211.040009
[ PSA ]:
46.17000
[ LogP ]:
1.82
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.579
[ Water Solubility ]:
<0.1 g/100 mL at 19 ºC
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AE1050000
- CHEMICAL NAME :
- Acetanilide, 4'-(chloroacetyl)-
- CAS REGISTRY NUMBER :
- 140-49-8
- BEILSTEIN REFERENCE NO. :
- 2724140
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H10-Cl-N-O2
- MOLECULAR WEIGHT :
- 211.66
- WISWESSER LINE NOTATION :
- G1VR DMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1470 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 3300 ng/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7(Suppl 5),1,1985
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
AE1050000
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%