bas 320i

Names

[ Name ]:
bas 320i

[Synonym ]:
FXFFOR DMVMNUY1R DCN&R CXFFF
(2E)-2-{2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene}-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide
Hydrazinecarboxamide, 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-, (2E)-

Biological Activity

[Description]:

Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel

Research Areas >> Infection

[Target]

Sodium channel[1]

[In Vitro]

Metaflumizone (10 μM) completely inhibits the Para/TipE sodium currents in Xenopus oocytes[1].

[References]

[1]. Salgado VL, et al. Metaflumizone is a novel sodium channel blocker insecticide. Vet Parasitol. 2007 Dec 15;150(3):182-9. Epub 2007 Oct 23.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₂₄H₁₆F₆N₄O₂

[ Molecular Weight ]:
506.40

[ Exact Mass ]:
506.117737

[ PSA ]:
86.51000

[ LogP ]:
6.05

[ Index of Refraction ]:
1.547

[ Storage condition ]:
2-8℃

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 3077 9 / PGIII

[ RTECS ]:
MV1576452

Articles

Two novel sodium channel mutations associated with resistance to indoxacarb and metaflumizone in the diamondback moth, Plutella xylostella.

Insect Sci. 23 , 50-8, (2016)

Indoxacarb and metaflumizone belong to a relatively new class of sodium channel blocker insecticides (SCBIs). Due to intensive use of indoxacarb, field-evolved indoxacarb resistance has been reported ...