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triptonoditerpenic acid

Names

[ CAS No. ]:
139953-20-1

[ Name ]:
triptonoditerpenic acid

[Synonym ]:
2-Phenanthrenecarboxylic acid,3,4,4a,9,10,10a-hexahydro-8-hydroxy-6-methoxy-1,4a-dimethyl-7-(1-methylethyl)
Triptonoditerpenic acid

Biological Activity

[Description]:


[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[Target]

IC50: 42.53 μM (HepG2), 29.74 μM (Hep3B), 37.63 μM (Bcap37)[1].


[In Vitro]

Triptonoditerpenic acid 对 HepG2、Hep3B 和 Bcap37 具有细胞毒性,IC50 值分别为 42.53 μM、29.74 μM 和 37.63 μM[1]。

[References]

[1]. Chang Gao, et al. Kaurane and abietane diterpenoids from the roots of Tripterygium wilfordii and their cytotoxic evaluation. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2942-2946.  

Chemical & Physical Properties

[ Density]:
1.159g/cm3

[ Boiling Point ]:
509.6ºC at 760mmHg

[ Molecular Formula ]:
C21H28O4

[ Molecular Weight ]:
344.44500

[ Flash Point ]:
176.1ºC

[ Exact Mass ]:
344.19900

[ PSA ]:
66.76000

[ LogP ]:
4.53920

[ Vapour Pressure ]:
3.28E-11mmHg at 25°C

[ Index of Refraction ]:
1.568


Related Compounds

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