L-Methionine [R,S]-Sulfoximine

Names

[ Name ]:
L-Methionine [R,S]-Sulfoximine

Biological Activity

[Description]:

N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) is a deuterium labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.

[2]. Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20.

[3]. Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21(8):1511-8.

[4]. Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₂D₃N₅O₄

[ Molecular Weight ]:
284.29

[ Appearance of Characters ]:
Solid | White to Pale Beige

[ Stability ]:
Hygroscopic

[ Water Solubility ]:
DMSO (Slightly), Methanol (Slightly)

Related Compounds

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