Propamocarb-d7

Names

[ CAS No. ]:
1398065-89-8

[ Name ]:
Propamocarb-d7

[Synonym ]:
Propamocarb-(propyl-d7)
MFCD04972577
Carbamic acid, N-[3-(dimethylamino)propyl]-, propyl-d7 ester
(2H7)Propyl [3-(dimethylamino)propyl]carbamate
Propamocarb-d7

Biological Activity

[Description]:

Propamocarb-d7 is the deuterium labeled Propamocarb[1]. Propamocarb is a systemic fungicide. Propamocarb is widely used to protect cucumbers, tomatoes and other plants from pathogens[2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Xin Liu , et al. Differential Responses of Larval Zebrafish to the Fungicide Propamocarb: Endpoints at Development, Locomotor Behavior and Oxidative Stress. Sci Total Environ. 2020 Aug 20;731:139136.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
272.3±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H13D7N2O2

[ Molecular Weight ]:
195.310

[ Flash Point ]:
118.5±22.6 °C

[ Exact Mass ]:
195.196411

[ LogP ]:
1.12

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.450

Related Compounds