Hydroxyhomo Sildenafil

Names

[ Name ]:
Hydroxyhomo Sildenafil

[Synonym ]:
hydroxyhomosildenafil
Hydroxyhomo Sildenafil

Biological Activity

[Description]:

Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED), with less oral bioavailability than Lodenafil carbonate[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)

[Target]

PDE5

[References]

[1]. Toque HA, et al. Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. Eur J Pharmacol. 2008 Sep 4;591(1-3):189-95.

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
730.6ºC at 760 mmHg

[ Melting Point ]:
183-185 °C

[ Molecular Formula ]:
C₂₃H₃₂N₆O₅S

[ Molecular Weight ]:
504.60200

[ Flash Point ]:
395.7ºC

[ Exact Mass ]:
504.21500

[ PSA ]:
142.03000

[ LogP ]:
1.93000

[ Vapour Pressure ]:
2.08E-22mmHg at 25°C

[ Index of Refraction ]:
1.667

Safety Information

[ Hazard Codes ]:
Xi

Hydroxyhomo Sildenafil

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds