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Bio-AMS

Names

[ CAS No. ]:
1393881-52-1

[ Name ]:
Bio-AMS

Biological Activity

[Description]:

Bio-AMS is a chemical inhibitor of Mycobacterium tuberculosis biotin protein ligase ( MtBPL) with Kd of 0.865 nM; possesses selective activity against Mycobacterium tuberculosis ( Mtb) and arrests fatty acid and lipid biosynthesis, enhances tuberculosis chemotherapy (rifampicin and ethambutol).

[References]

References 1. Tiwari D, et al. Sci Transl Med. 2018 Apr 25;10(438). pii: eaal1803. 2. Bockman MR, et al. ACS Infect Dis. 2018 Apr 17. doi: 10.1021/acsinfecdis.8b00038. View Related Products by Target Bacterial

Chemical & Physical Properties

[ Molecular Formula ]:
C20H29N9O7S2

[ Molecular Weight ]:
571.628


Related Compounds