Temelimab

Names

[ Name ]:
Temelimab

Biological Activity

[Description]:

Temelimab (GNbAC-1) is an IgG4 monoclonal antibody that targets the human endogenous retroviral envelope protein HERV-W-Env[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[In Vitro]

Temelimab 在体内安全且耐受性良好[1]。

[References]

[1]. Kornmann G, et, al. Temelimab, an IgG4 Anti-Human Endogenous Retrovirus Monoclonal Antibody: An Early Development Safety Review. Drug Saf. 2020 Dec;43(12):1287-1296.

[2]. Hartung HP, et, al. Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study. Mult Scler. 2022 Mar;28(3):429-440.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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