2-PMDQ

Names

[ Name ]:
2-PMDQ

[Synonym ]:
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

Biological Activity

[Description]:

AT-112 is a ketotanserin analogue. AT-112 has hemodynamic effects. AT-112 significantly reduces portal vein branch blood flow and portal vein pressure. AT-112 can be used to study the pathogenesis of portal hypertension[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Lin HC, et al The hemodynamic effects of AT-112, an analog of ketanserin, in portal hypertensive rats. Pharmacology. 1997 Jan;54(1):16-23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₃N₅O

[ Molecular Weight ]:
361.44

[ Exact Mass ]:
361.19000

[ PSA ]:
56.63000

[ LogP ]:
0.87320

Related Compounds

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