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Isocoronarin D

Names

[ CAS No. ]:
138965-88-5

[ Name ]:
Isocoronarin D

[Synonym ]:
isocoronarin D
Isoconazol
Fazol
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E)-
Travogen
Isoconazole
(3E)-4-Hydroxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
Isoconazolum

Biological Activity

[Description]:

Isocoronarin D is a diterpene that can be isolated from rhizomes of Hedychium coronarium. Isocoronarin D can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Hsieh MY, et al. Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway. Biomed Pharmacother. 2020 Aug;128:110318.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
468.4±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H30O3

[ Molecular Weight ]:
318.450

[ Flash Point ]:
187.7±21.5 °C

[ Exact Mass ]:
318.219482

[ PSA ]:
46.53000

[ LogP ]:
5.31

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.535

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds