KDM5B-IN-3

Names

[ CAS No. ]:
1385101-10-9

[ Name ]:
KDM5B-IN-3

Biological Activity

[Description]:

KDM5B-IN-3 (Compound 5) is a histone lysine specific demethylase 5B (KDM5B/JARID1B) inhibitor with an IC50 of 9.32 μM. KDM5B-IN-3 can be used for the research of gastric cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Demethylase

[References]

[1]. Bing Zhao, et al. Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B). Eur J Med Chem. 2020 Apr 15;192:112161.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H25ClN4O2

[ Molecular Weight ]:
376.88

Related Compounds

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