BMS-984923
Names
[ CAS No. ]:
1375752-78-5
[ Name ]:
BMS-984923
Biological Activity
[Description]:
BMS-984923, a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling.
Chemical & Physical Properties
[ Molecular Formula ]:
C22H15ClN2O2
[ Molecular Weight ]:
374.82
Related Compounds
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