Vitacoxib

Names

[ Name ]:
Vitacoxib

[Synonym ]:
Pyridine, 2-[4-chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)-
2-[4-Chloro-5-(4-methylphenyl)-1H-imidazol-1-yl]-5-(methylsulfonyl)pyridine

Biological Activity

[Description]:

A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL); a novel nonsteroidal anti-inflammatory drugs for veterinary use.

[References]

References 1. Wang J, et al. Regul Toxicol Pharmacol. 2017 Jun;86:49-58. 2. Wang J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:270-274. View Related Products by Target Cyclooxygenase (COX)

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
582.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₄ClN₃O₂S

[ Molecular Weight ]:
347.819

[ Flash Point ]:
305.9±30.1 °C

[ Exact Mass ]:
347.049530

[ LogP ]:
1.87

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.655

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.