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Dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate

Names

[ CAS No. ]:
1369427-40-6

[ Name ]:
Dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate

[Synonym ]:
(2R,3R)-3-Methoxy-2-methyl-3-[(2S)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-pyrrolidinyl]propanoic acid - N-cyclohexylcyclohexanamine (1:1)
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
MFCD31560448

Biological Activity

[Description]:

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H48N2O5

[ Molecular Weight ]:
468.68

[ Exact Mass ]:
468.356323

Related Compounds