changnanic acid

Names

[ CAS No. ]:
136040-44-3

[ Name ]:
changnanic acid

[Synonym ]:
(Z)-(R)-6-[(3S,3aR,4aS,6aR,7R,9aS,9bS)-3a-(2-Carboxy-ethyl)-3-isopropenyl-6a,9a-dimethyl-3a,4,5,6,6a,7,8,9,9a,9b-decahydro-3H-cyclopenta[a]cyclopropa[e]naphthalen-7-yl]-2-methyl-hept-2-enoic acid

Biological Activity

[Description]:

Changnanic acid (schisandrin) is a triterpene compound with potential anti-tumor effects. Changnanic acid exhibits moderate cytotoxic activity against human tumor cell lines Bel-7402, MCF-7 and HL-60, with IC50s of 100 μM, 100 μM and 50.51 μM respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Wang W, et al. New triterpenoids from Kadsura heteroclita and their cytotoxic activity. Planta Med. 2006 Apr;72(5):450-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C30H44O4

[ Molecular Weight ]:
468.66800

[ Exact Mass ]:
468.32400

[ PSA ]:
74.60000

[ LogP ]:
7.26960

Related Compounds

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