Alkaloid XC-99
Names
[ CAS No. ]:
1355-31-3
[ Name ]:
Alkaloid XC-99
[Synonym ]:
4',5'-Didehydro-4'-deoxy-2',19'-dioxo-2',19'-secovincaleukoblastine
4-acetoxy-15-(9-ethyl-7-formyl-13-methoxycarbonyl-11-oxo-5,6,7,10,11,12,13,14-octahydro-7,14-diaza-cycloundeca[a]inden-13-yl)-3-hydroxy-16-methoxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester
Chemical & Physical Properties
[ Density]:
1.37g/cm3
[ Boiling Point ]:
912.8ºC at 760 mmHg
[ Molecular Formula ]:
C46H54N4O10
[ Molecular Weight ]:
822.94200
[ Flash Point ]:
505.9ºC
[ Exact Mass ]:
822.38400
[ PSA ]:
168.01000
[ LogP ]:
4.81610
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.663
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VS3630000
- CHEMICAL NAME :
- 2',19'-Secovincaleukoblastine, 4',5'-didehydro-4'-deoxy-2',19'-dioxo
- CAS REGISTRY NUMBER :
- 1355-31-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C46-H54-N4-O10
- MOLECULAR WEIGHT :
- 823.04
- WISWESSER LINE NOTATION :
- T C6 B5665 2AB S BX IN QN JH&&TTTJ FO1 I1 KVO1 LOV1 M2 E- JT B65-11- HM PNV NU&TTJ JVO1 N2 P1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- 33GVAL "Catharanthus Alkaloids," Taylor, W.I., and N.R. Farnsworth, eds., New York, Marcel Dekker, 1975 Volume(issue)/page/year: -,72,1975