DC44

Names

[ Name ]:
DC44

Biological Activity

[Description]:

DC44, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44 can be used for the targeted treatment of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

[In Vitro]

DC44 can be conjugated to the humanized monoclonal antibody huB4 by a linker SPP to form huB4-SPP-DC44[1].

[References]

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₃₅ClN₅O₇PS

[ Molecular Weight ]:
760.19

Related Compounds

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