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Biotin-PEG6-acid

Names

[ CAS No. ]:
1352814-10-8

[ Name ]:
Biotin-PEG6-acid

[Synonym ]:
4,7,10,13,16,19-Hexaoxa-22-azaheptacosan-1-oic acid, 27-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-23-oxo-
23-Oxo-27-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13,16,19-hexaoxa-22-azaheptacosan-1-oic acid
MFCD16875661

Biological Activity

[Description]:

Biotin-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
818.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H45N3O10S

[ Molecular Weight ]:
579.704

[ Flash Point ]:
448.8±34.3 °C

[ Exact Mass ]:
579.282593

[ LogP ]:
-2.48

[ Vapour Pressure ]:
0.0±6.4 mmHg at 25°C

[ Index of Refraction ]:
1.508

Related Compounds