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ABBV-167

Names

[ CAS No. ]:
1351456-78-4

[ Name ]:
ABBV-167

Biological Activity

[Description]:

ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family
Research Areas >> Cancer

[References]

[1]. Salem AH, et al. Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Mol Cancer Ther. 2021 Jun;20(6):999-1008.

Chemical & Physical Properties

[ Molecular Formula ]:
C46H53ClN7O11PS

[ Molecular Weight ]:
978.45

Related Compounds