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JQ-35, (S)-

Names

[ CAS No. ]:
1349719-98-7

[ Name ]:
JQ-35, (S)-

[Synonym ]:
2-[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-[3-(4-methyl-1-piperazinyl)propyl]acetamide
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-2,3,9-trimethyl-N-[3-(4-methyl-1-piperazinyl)propyl]-, (6S)-
(S)-jq-35

Biological Activity

[Description]:

JQ-35, (S)- is an inhibitor of the Bromodomain and Extra-Terminal (BET) family bromodomain-containing proteins with potential antineoplastic activity.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Research Areas >> Cancer

[Related Small Molecules]

(+)-JQ1 | GSK126 | Tazemetostat (EPZ-6438) | Birabresib (OTX015) | A 485 | Curcumin | ARV-771 | ARV-825 | I-BET762 | BI 2536 | GSK343 | C646 | 3-Deazaneplanocin A (hydrochloride) | I-BET151 | 666-15

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C27H34ClN7OS

[ Molecular Weight ]:
540.123

[ Exact Mass ]:
539.223389

[ LogP ]:
1.73

[ Index of Refraction ]:
1.694

Related Compounds