NSC639828

Names

[ Name ]:
NSC639828

Biological Activity

[Description]:

NSC639828 is a potent inhibitor of DNA polymerase with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for the treatment of cancer disease[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

DNA polymerase[1].

[References]

[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.

Chemical & Physical Properties

[ Density]:
1.663g/cm3

[ Molecular Formula ]:
C₁₈H₁₃BrClN₅O₃

[ Molecular Weight ]:
462.68500

[ Exact Mass ]:
460.98900

[ PSA ]:
119.23000

[ LogP ]:
5.27400

[ Index of Refraction ]:
1.708

Related Compounds

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