SDKPDMAEIEKFDKSK

Names

[ CAS No. ]:
1339864-27-5

[ Name ]:
SDKPDMAEIEKFDKSK

Biological Activity

[Description]:

SDKPDMAEIEKFDKSK is a peptide derived from thymosin β4 (Tβ4)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

Thymosin β4 (Tβ4) is a 43 amino acid polypeptide that belongs to a large family of highly conserved, small biologically active molecules. Thymosin β4 (Tβ4) inhibits PDGF-BB-induced fibrogenesis, proliferation and migration of HSC by blocking Akt phosphorylation[1].

[References]

[1]. Shah R, et al. Thymosin β4 inhibits PDGF-BB induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain. Expert Opin Biol Ther. 2018;18(sup1):177-184.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈₀H₁₃₀N₂₀O₂₉S

[ Molecular Weight ]:
1868.07

Related Compounds

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