Epoxiconazole

Names

[ Name ]:
Epoxiconazole

[Synonym ]:
Opal 7.5 EC
1-{[3-(2-Chlorphenyl)-2-(4-fluorphenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazol
1-[[3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole
1-{[3-(2-Chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl}-1H-1,2,4-triazole
1H-1,2,4-Triazole, 1-[[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-
OPUS
(2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole
Epoxiconazole
1-{[3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole

Biological Activity

[Description]:

Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Yabing Duan, et al. Impact of Epoxiconazole on Fusarium Head Blight Control, Grain Yield and Deoxynivalenol Accumulation in Wheat. Pestic Biochem Physiol. 2018 Nov;152:138-147.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
463.1±55.0 °C at 760 mmHg

[ Melting Point ]:
125°C (lit.)

[ Molecular Formula ]:
C₁₇H₁₃ClFN₃O

[ Molecular Weight ]:
329.756

[ Flash Point ]:
233.9±31.5 °C

[ Exact Mass ]:
329.073120

[ PSA ]:
43.24000

[ LogP ]:
3.44

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.659

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H351-H360Df-H411

[ Precautionary Statements ]:
P201-P273-P308 + P313-P391-P501

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
R40;R51/53;R62;R63

[ Safety Phrases ]:
36/37-46-61

[ RIDADR ]:
UN 3077

[ RTECS ]:
XZ4500100

[ HS Code ]:
2933199090

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

PLoS ONE 6(6) , e20973, (2011)

A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homo...

Enantiomeric separation of triazole fungicides with 3-μm and 5-μml particle chiral columns by reverse-phase high-performance liquid chromatography.

Chirality 23(6) , 479-86, (2011)

This study used chiral columns packed with 3-μm and 5-μm particles to comparatively separate enantiomers of 9 triazole fungicides, and Lux Cellulose-1 columns with chiral stationary phase of cellulose...

Inhibition of efflux transporter-mediated fungicide resistance in Pyrenophora tritici-repentis by a derivative of 4'-hydroxyflavone and enhancement of fungicide activity.

Appl. Environ. Microbiol. 71(6) , 3269-75, (2005)

Populations of the causal agent of wheat tan spot, Pyrenophora tritici-repentis, that are collected from fields frequently treated with reduced fungicide concentrations have reduced sensitivity to str...