(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester

Names

[ Name ]:
(S)-2-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphorylamino]propionic acid isopropyl ester

[Synonym ]:
.(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
.(S)-isopropyl-2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
.2(S)-[((R)-2,3,4,5,6-pentafluoro-phenoxy)-phenoxy-phosphorylamino]propionic acid isopropyl ester
.(S)-isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate
propan-2-yl (2S)-2-[[(R)-pentafluorophenoxy(phenoxy)phosphoryl]amino]propanoate

Biological Activity

[Description]:

Isopropyl ((R)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate can be used to synthesis Sofosbuvir (HY-15005) to avoid the production of sofibuvir degradation impurities[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Shi GH, et al. The preparation of Suo Feibuwei. CN109535213A.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₇F₅NO₅P

[ Molecular Weight ]:
453.29700

[ Exact Mass ]:
453.07600

[ PSA ]:
83.67000

[ LogP ]:
5.26860