heudelotinone

Names

[ Name ]:
heudelotinone

[Synonym ]:
BL-P1761
Hetacillin-methoxymethylester
Sarpicillina
heteroclitin D
(11aR)-7-Hydroxy-1,1,8-trimethyl-1,10,11,11a-tetrahydro-2H-dibenzo[a,d][7]annulen-2-one
Sarpicillinum
Sarpicilline
Sarpicillin
2H-Dibenzo[a,d]cyclohepten-2-one, 1,10,11,11a-tetrahydro-7-hydroxy-1,1,8-trimethyl-, (11aR)-
heudelotinone

Biological Activity

[Description]:

Heudelotinone is a dinorditerpenoid that can be isolated from the stem bark and roots of Ricinodendron heudelotii. Heudelotinone shows cytotoxicity against SMMC-7721, A549 and Hela cells with IC50s of 21.68, 16.04 and 10.67 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Samuel F. Kimbu, et al. Two dinorditerpenoids from Ricinodendron heudelotii. Phytochemistry. 1991, Pages 619-621.

[2]. Jun-Ju Xu, et al. A New Tetracyclic Diterpene from Jatropha curcas. 10 May 2011.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
471.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₀O₂

[ Molecular Weight ]:
268.350

[ Flash Point ]:
200.4±21.3 °C

[ Exact Mass ]:
268.146332

[ PSA ]:
37.30000

[ LogP ]:
3.86

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.608

Safety Information

[ Hazard Codes ]:
Xi