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OSU-T315

Names

[ CAS No. ]:
1333146-24-9

[ Name ]:
OSU-T315

[Synonym ]:
compound 22 [PMID: 21823616]
N-Methyl-3-{1-[4-(1-piperazinyl)phenyl]-5-[4'-(trifluoromethyl)-4-biphenylyl]-1H-pyrazol-3-yl}propanamide
1H-Pyrazole-3-propanamide, N-methyl-1-[4-(1-piperazinyl)phenyl]-5-[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]-
MFCD29472239

Biological Activity

[Description]:

OSU-T315 is an inhibitor of integrin-linked kinase (ILK) with an IC50 of 600 nM.

[Related Catalog]:

Signaling Pathways >> Cytoskeleton >> Integrin
Research Areas >> Cancer

[Related Small Molecules]

Cilengitide | Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt | Arg-Gly-Asp-Ser | CWHM-12 | E 7820 | GLPG 0187 | Firategrast | ATN-161 trifluoroacetate salt | Cucurbitacin B | Eptifibatide acetate salt | iRGD peptide | Lifitegrast | Zaurategrast | Integrin Antagonist 1 (hydrochloride) | TR 14035

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
739.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H30F3N5O

[ Molecular Weight ]:
533.587

[ Flash Point ]:
400.9±32.9 °C

[ Exact Mass ]:
533.240234

[ LogP ]:
4.65

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.615

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds