2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine

Names

[ Name ]:
2-Ethyl-5,7-Dimethyl-3H-Imidazo[4,5-B]Pyridine

[Synonym ]:
5,7-dimethyl-2-ethyl-imidazo<4,5-b>pyridine
5,7-dimethyl-2-ethyl-3H-imidazo<4,5-b>pyridine

Biological Activity

[Description]:

Adenosine receptor antagonist 4 (compound 2) is an adenosine A1 receptor antagonist with a Ki of 101 nM for human A1 receptor[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor

[References]

[1]. Lisa C W Chang, et al. 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. J Med Chem. 2007 Feb 22;50(4):828-34.

Chemical & Physical Properties

[ Density]:
1.14g/cm3

[ Boiling Point ]:
370.502ºC at 760 mmHg

[ Melting Point ]:
142-146 °C

[ Molecular Formula ]:
C₁₀H₁₃N₃

[ Molecular Weight ]:
175.23

[ Flash Point ]:
174.175ºC

[ Exact Mass ]:
175.11100

[ PSA ]:
41.57000

[ LogP ]:
2.13710

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.619

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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