2-TEDC

Names

[ Name ]:
2-TEDC

[Synonym ]:
2,6-dichloro-5-fluoronicotinoyl chloride
2-tedc

Biological Activity

[Description]:

2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase

Research Areas >> Metabolic Disease

[Target]

IC50: 0.09 μM (5-lipoxygenase); 0.013 μM (12-lipoxygenase); 0.5 μM (15-lipoxygenase)[1].

[In Vitro]

2-TEDC can potent inhibit 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₃NO₄S

[ Molecular Weight ]:
315.34400

[ Exact Mass ]:
315.05700

[ PSA ]:
118.79000

[ LogP ]:
2.85218

Precursor & DownStream

Precursor

DownStream

Related Compounds

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