4-Methylthio benzoic acid
Names
[ CAS No. ]:
13205-48-6
[ Name ]:
4-Methylthio benzoic acid
[Synonym ]:
4-Methylthio benzoic acid
4-methylsulfanylbenzoic acid
MFCD00002555
4-(Methylsulfanyl)benzoic acid
Benzoic acid, 4-(methylthio)-
4-(Methylmercapto)benzoic acid
4-(methylthio)benzoic acid
EINECS 236-171-5
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
319.0±25.0 °C at 760 mmHg
[ Melting Point ]:
192-196 °C(lit.)
[ Molecular Formula ]:
C8H8O2S
[ Molecular Weight ]:
168.213
[ Flash Point ]:
146.7±23.2 °C
[ Exact Mass ]:
168.024506
[ PSA ]:
62.60000
[ LogP ]:
2.74
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.613
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Biochem. Pharmacol. 41(12) , 1997-2003, (1991)
Administration of 4-methylthiobenzoic acid (MTBA) (100 mg/kg) strongly reduced cisplatin nephrotoxicity (7.5 mg/kg, 20 min after MTBA) in rats as determined by histopathology and blood urea nitrogen. ...
Preventive action of thioethers towards in vitro DNA binding and mutagenesis in E. coli K12 by alkylating agents.Mutat. Res. 245(2) , 67-74, (1990)
Thioethers are effective scavengers of electrophilic metabolites derived from the hepatocarcinogen N-hydroxy-2-acetylaminofluorene (van den Goorbergh et al., 1987). In this study 2 of these thioethers...