1-Methyl-3-(alpha-Cyclopentylmandeloyloxy)Pyrrolidinehydrochloride
Names
[ CAS No. ]:
13118-10-0
[ Name ]:
1-Methyl-3-(alpha-Cyclopentylmandeloyloxy)Pyrrolidinehydrochloride
[Synonym ]:
Mandelic acid,1-methyl-3-pyrrolidinyl ester,hydrochloride
AHR-376
1-Methyl-3-(alpha-Cyclopentylmandeloyloxy)Pyrrolidinehydrochloride
Chemical & Physical Properties
[ Density]:
1.17g/cm3
[ Boiling Point ]:
434.6ºC at 760mmHg
[ Molecular Formula ]:
C18H26ClNO3
[ Molecular Weight ]:
339.85700
[ Flash Point ]:
216.7ºC
[ Exact Mass ]:
339.16000
[ PSA ]:
49.77000
[ LogP ]:
3.05160
[ Vapour Pressure ]:
2.52E-08mmHg at 25°C
[ Index of Refraction ]:
1.577
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OO7340000
- CHEMICAL NAME :
- Mandelic acid, alpha-cyclopentyl-, 1-methyl-3-pyrrolidinyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 13118-10-0
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C18-H25-N-O3.Cl-H
- MOLECULAR WEIGHT :
- 339.90
- WISWESSER LINE NOTATION :
- T5NTJ A1 COVXQR&- AL5TJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 14 ug/kg/D
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Behavioral - toxic psychosis
- REFERENCE :
- CPAJAK Canadian Psychiatric Association Journal. (Ottawa, Ont., Canada) V.1-23, 1956-78. For publisher information, see CJPSDF. Volume(issue)/page/year: 11,S141,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,523,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 2,523,1960