Urolithin D

Names

[ Name ]:
Urolithin D

[Synonym ]:
6H-Dibenzo[b,d]pyran-6-one, 3,4,8,9-tetrahydroxy-
3,4,8,9-Tetrahydroxy-6H-benzo[c]chromen-6-one
3,4,8,9-Tetrahydroxybenzo[c]chromen-6-one
6H-Dibenzo(b,d)pyran-6-one, 3,4,8,9-tetrahydroxy-
urolithin D

Biological Activity

[Description]:

Urolithin D is competitive and reversible antagonist of EphA receptors. Urolithin D exhibits intra-classes selectivity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ephrin Receptor

[References]

[1]. Giorgio C, et al. The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells. Mol Nutr Food Res. 2015 Nov;59(11):2155-67.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
634.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₈O₆

[ Molecular Weight ]:
260.20

[ Flash Point ]:
253.0±25.0 °C

[ Exact Mass ]:
260.032074

[ PSA ]:
111.13000

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.801

Synthetic Route

Click to get detail synthetic route

Related Compounds

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