1-Nitroso-2-naphthol
Names
[ CAS No. ]:
131-91-9
[ Name ]:
1-Nitroso-2-naphthol
[Synonym ]:
Nitroso-2-Naphthol
Zelen moridlova 4
ortho-hydroxynitrosonaphthalene
1-NITROSO-2-NAPTHOL
1-Nitroso-2-naphthol
1-nitroso-2-naphtho
1-nitroso-2-hydroxy-naphthalene
1-Nitroso-2-naphthalenol
1-Nitroso-2-naftol
2-hydroxy-1-nitrosonaphthalene
Nitroso-β-naphthol
EINECS 205-043-0
2-Naphthalenol, 1-nitroso-
MFCD00003884
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
357.6±25.0 °C at 760 mmHg
[ Melting Point ]:
106-108 °C (dec.)(lit.)
[ Molecular Formula ]:
C10H7NO2
[ Molecular Weight ]:
173.168
[ Flash Point ]:
170.1±23.2 °C
[ Exact Mass ]:
173.047684
[ PSA ]:
49.66000
[ LogP ]:
2.42
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.630
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL4725000
- CHEMICAL NAME :
- 2-Naphthol, 1-nitroso-
- CAS REGISTRY NUMBER :
- 131-91-9
- BEILSTEIN REFERENCE NO. :
- 0776947
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C10-H7-N-O2
- MOLECULAR WEIGHT :
- 173.18
- WISWESSER LINE NOTATION :
- L66J BNO CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA repair
- TEST SYSTEM :
- Bacteria - Bacillus subtilis
- DOSE/DURATION :
- 10 mmol/L
- REFERENCE :
- JNSVA5 Journal of Nutritional Science and Vitaminology. (Business Center for Academic Soc. Japan, 2-4-16 Yayoi, Bunkyo-ku, Tokyo 113, Japan) V.19- 1973- Volume(issue)/page/year: 25,317,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82063 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1215 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82063 No. of Facilities: 20 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 799 (estimated) No. of Female Employees: 655 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R33
[ Safety Phrases ]:
S26-S36-S45
[ RIDADR ]:
UN3077
[ WGK Germany ]:
3
[ RTECS ]:
QL4725000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
[ HS Code ]:
29089000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2908999090
[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Chem. Pharm. Bull. 30(1) , 358-61, (1982)
Determination of urinary homovanillic acid using the nitrosonaphthol reaction.
Am. J. Clin. Pathol. 87(5) , 644-8, (1987)
Determination of urinary homovanillic acid (HVA) is an important analysis to establish the diagnosis and prognosis of neuroblastoma. A method is presented for the determination of this metabolite of d...
Improved quantitation for urinary 5-hydroxyindole acetate using the nitrosonaphthol reaction.Clin. Biochem. 17(1) , 37-8, (1984)