VU0361747

Names

[ Name ]:
VU0361747

Biological Activity

[Description]:

VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).

[References]

1. Rook JM, Noetzel MJ, Pouliot WA, Bridges TM, Vinson PN, Cho HP, Zhou Y, Gogliotti RD, Manka JT, Gregory KJ, Stauffer SR, Dudek FE, Xiang Z, Niswender CM, Daniels JS, Jones CK, Lindsley CW, Conn PJ. Unique signaling profiles of positive allosteric modulators of metabotropic glutamate receptor subtype 5 determine differences in in vivo activity. Biol Psychiatry. 2013 Mar 15;73(6):501-9. doi: 10.1016/j.biopsych.2012.09.012. Epub 2012 Nov 7. PubMed PMID: 23140665; PubMed Central PMCID: PMC3572342.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₇FN₂O₂

[ Molecular Weight ]:
324.35

Related Compounds

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