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GPR40 Activator 1

Names

[ CAS No. ]:
1309435-60-6

[ Name ]:
GPR40 Activator 1

[Synonym ]:
GPR40 Activator 1

Biological Activity

[Description]:

GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.IC50 value:Target: GPR40Preparation of spiropiperidine derivatives for use as antidiabetic agentsBy Hamdouchi, Chafiq; Lineswala, Jayana Pankaj; Maiti, Pranab From PCT Int. Appl. (2011), WO 2011066183 A1 20110603.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GPR40
Research Areas >> Metabolic Disease

[References]

[1]. Novel spiropiperidine compounds , Patent WO 2011066183 A1


[Related Small Molecules]

TAK-875 | GW-1100 | GW9508 | DC 260126 | PBI-4050 sodium salt | GPR40 Activator 2 | TUG-770 | AMG 837 | FAA1 agonist-1 | AM-1638 | GPR40 Agonist 2

Chemical & Physical Properties

[ Molecular Formula ]:
C31H31NO3S

[ Molecular Weight ]:
497.64800

[ Exact Mass ]:
497.20200

[ PSA ]:
78.01000

[ LogP ]:
6.40720

[ Storage condition ]:
2-8℃

Related Compounds