GRP-60367

Names

[ Name ]:
GRP-60367

Biological Activity

[Description]:

GRP-60367 is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[Target]

RABV[1]

[In Vitro]

GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52 nM on different host cell lines[1].

[References]

[1]. Venice Du Pont, et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor. J Virol. 2020 Jun 16;94(13):e00321-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₇N₃O₂

[ Molecular Weight ]:
353.46

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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