L 669262

Names

[ Name ]:
L 669262

[Synonym ]:
l-669,262

Biological Activity

[Description]:

L-669,262, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, with an IC50 of 0.10 ng/mL for rat liver HMG-CoA[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)

Research Areas >> Metabolic Disease

[References]

[1]. Joshua H, et, al. L-669,262, a potent HMG-CoA reductase inhibitor. J Antibiot (Tokyo). 1991 Mar;44(3):366-70.

Chemical & Physical Properties

[ Density]:
1.16g/cm3

[ Boiling Point ]:
609.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₅H₃₆O₆

[ Molecular Weight ]:
432.55

[ Flash Point ]:
202.1ºC

[ Exact Mass ]:
432.25100

[ PSA ]:
89.90000

[ LogP ]:
3.90870

[ Vapour Pressure ]:
2.11E-17mmHg at 25°C

[ Index of Refraction ]:
1.536

Related Compounds

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