Fmoc-D-Tic-OH

Names

[ Name ]:
Fmoc-D-Tic-OH

[Synonym ]:
Fmoc-D-Tic-OH
(3R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
(R)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
(3R)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
2,3(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(9H-fluoren-9-ylmethyl) ester, (3R)-
MFCD00144345
2,3(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(9H-fluoren-9-ylmethyl) ester

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
629.9±55.0 °C at 760 mmHg

[ Melting Point ]:
160-164 °C

[ Molecular Formula ]:
C₂₅H₂₁NO₄

[ Molecular Weight ]:
399.439

[ Flash Point ]:
334.7±31.5 °C

[ Exact Mass ]:
399.147064

[ PSA ]:
66.84000

[ LogP ]:
4.84

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.657

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity.

J. Med. Chem. 39 , 1472, (1996)

We report a systematic probing of the structural requirements of the bradykinin (BK) type 2 (B(2)) receptor for antagonist activity by incorporating N-alkyl-amino acid residues at positions 7 and 8 of...

Design and synthesis of new linear and cyclic bradykinin antagonists.

J. Med. Chem. 39 , 2095, (1996)

We report here on the synthesis and pharmacological properties of a new series of small linear and cyclic peptides derived from the five C-terminal amino acid residues of second-generation bradykinin ...