Oncaspar

Names

[ Name ]:
Oncaspar

[Synonym ]:
(3β,7α)-7-Hydroperoxycholest-5-en-3-ol
Cholest-5-en-3-ol, 7-hydroperoxy-, (3β,7α)-

Biological Activity

[Description]:

Oncaspar (PEG-L-asparaginase; Pegasparaginase), a pegylated form of native Escherichia coli-derived L-asparaginase, breaks down the amino acid asparagine that are circulating in the bloodstream. Oncaspar plays an important role in acute lymphoblastic leukemia (ALL)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Young-A Heo, et al. Pegaspargase: A Review in Acute Lymphoblastic Leukaemia.Drugs. 2019 May;79(7):767-777.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
534.2±39.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₄₆O₃

[ Molecular Weight ]:
418.652

[ Flash Point ]:
276.8±27.1 °C

[ Exact Mass ]:
418.344696

[ LogP ]:
8.83

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.536