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Eberconazole nitrate

Names

[ CAS No. ]:
130104-32-4

[ Name ]:
Eberconazole nitrate

[Synonym ]:
1H-Imidazole, 1-(2,4-dichloro-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-, nitrate (1:1)
1-(2,4-Dichloro-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-1H-imidazole nitrate (1:1)
Eberconazole nitrate

Biological Activity

[Description]:

Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more active than Clotrimazole, Ketoconazole, and Miconazole. Eberconazole nitrate has the potential for the research of dermatophytoses with a topical administration[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Fernández-Torres B, et al. In vitro activities of the new antifungal drug eberconazole and three other topical agents against 200 strains of dermatophytes. J Clin Microbiol. 2003;41(11):5209-5211.

Chemical & Physical Properties

[ Boiling Point ]:
495ºC at 760 mmHg

[ Molecular Formula ]:
C18H15Cl2N3O3

[ Molecular Weight ]:
392.236

[ Flash Point ]:
253.2ºC

[ Exact Mass ]:
391.049042

[ PSA ]:
83.87000

[ LogP ]:
5.10170

[ Vapour Pressure ]:
1.86E-09mmHg at 25°C

Related Compounds