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[Tyr(P)4] Angiotensin II

Names

[ CAS No. ]:
129785-85-9

[ Name ]:
[Tyr(P)4] Angiotensin II

[Synonym ]:
L-Phenylalanine, L-α-aspartyl-N-(diaminomethylene)-L-ornithyl-L-valyl-O-phosphono-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-
L-α-Aspartyl-N-(diaminomethylene)-L-ornithyl-L-valyl-O-phosphono-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine

Biological Activity

[Description]:

[Tyr(P)4] Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor
Research Areas >> Metabolic Disease

[References]

[1]. E A Kitas, et al. Chemical synthesis of an O-phosphorylated tyrosine analogue of human angiotensin II, [Tyr(P)4] angiotensin II, and its vasoconstrictor effect in intact sheep. Pept Res. Jul-Aug 1993;6(4):205-10.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C50H72N13O15P

[ Molecular Weight ]:
1126.16000

[ Exact Mass ]:
1125.50000

[ PSA ]:
462.68000

[ LogP ]:
1.04

[ Index of Refraction ]:
1.670


Related Compounds

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