RIPK2 inhibitor 1
Names
[ CAS No. ]:
1290490-78-6
[ Name ]:
RIPK2 inhibitor 1
[Synonym ]:
Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-
3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide
MFCD31746634
Biological Activity
[Description]:
RIPK2 inhibitor 1 is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM; potently inhibits the proliferation of cancer cells by > 70% and also inhibits NF-κB activity.
[References]
References 1. Salla M, et al. J Pharmacol Exp Ther. 2018 May;365(2):354-367. View Related Products by Target RIP kinase
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Molecular Formula ]:
C25H22N4O2
[ Molecular Weight ]:
410.468
[ Exact Mass ]:
410.174286
[ LogP ]:
3.46
[ Index of Refraction ]:
1.641