RIPK2 inhibitor 1

Names

[ Name ]:
RIPK2 inhibitor 1

[Synonym ]:
Benzamide, 3-(benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]-
3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide
MFCD31746634

Biological Activity

[Description]:

RIPK2 inhibitor 1 is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM; potently inhibits the proliferation of cancer cells by > 70% and also inhibits NF-κB activity.

[References]

References 1. Salla M, et al. J Pharmacol Exp Ther. 2018 May;365(2):354-367. View Related Products by Target RIP kinase

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C₂₅H₂₂N₄O₂

[ Molecular Weight ]:
410.468

[ Exact Mass ]:
410.174286

[ LogP ]:
3.46

[ Index of Refraction ]:
1.641

Related Compounds

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