Zymosterol

Names

[ CAS No. ]:
128-33-6

[ Name ]:
Zymosterol

[Synonym ]:
Zymosterol
(3S,5S,10S,13R,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Cholest-8,24-dien-3b-ol
5alpha-Cholesta-8,24-dien-3beta-ol
delta8,24-Cholestadien-3beta-ol
zymostrol
Cholesta-8,24-dien-3-ol
EINECS 204-880-9

Biological Activity

[Description]:

Zymosterol is a Cholesterol (HY-N0322) biosynthesis metabolite. Zymosterol, a precursor of Cholesterol, is found mostly in the plasma membrane. Zymosterol circulates within the cell[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

在人类成纤维细胞中，Zymosterol 仅在粗内质网中转化为胆固醇[2]。

[References]

[1]. Jena PK, et al. Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function. Biomark Res. 2020 Nov 6;8(1):59.

[2]. Lange Y, et al. Movement of zymosterol, a precursor of cholesterol, among three membranes in human fibroblasts. J Biol Chem. 1991 Nov 15;266(32):21439-43.

Chemical & Physical Properties

[ Density]:
1g/cm3

[ Boiling Point ]:
482.6ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₄₄O

[ Molecular Weight ]:
384.63800

[ Flash Point ]:
209.1ºC

[ Exact Mass ]:
384.33900

[ PSA ]:
20.23000

[ LogP ]:
7.45290

[ Vapour Pressure ]:
2.45E-11mmHg at 25°C

[ Index of Refraction ]:
1.535

Related Compounds

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