Benzyl DC-81

Names

[ CAS No. ]:
127810-79-1

[ Name ]:
Benzyl DC-81

[Synonym ]:
.Bn ether of DC-81
.DC-81 benzyl ether
.8-benzyl DC-81
.8-benzyloxy-7-methoxypyrrolo[2,1-c][1,4]benzodiazepin-5-one
.(11aS)-8-benzyloxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one
(11aS)-8-benzyloxy-7-methoxy-1,2,3-trihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one

Biological Activity

[Description]:

Benzyl DC-81 (Compound 6a) is an anticancer agent with antiproliferative activity against A375 and MCF-7 cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Adiyala PR, et al. Development of pyrrolo[2,1-c][1,4]benzodiazepine β-glucoside prodrugs for selective therapy of cancer. Bioorg Chem. 2018 Feb;76:288-293.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H20N2O3

[ Molecular Weight ]:
336.38

[ Exact Mass ]:
336.14700

[ PSA ]:
51.13000

[ LogP ]:
2.96820

Precursor & DownStream

Precursor

DownStream

Related Compounds

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