Methylenedihydrotanshinquinone

Names

[ Name ]:
Methylenedihydrotanshinquinone

[Synonym ]:
(1R)-1-Methyl-6-methylene-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione
Phenanthro[1,2-b]furan-10,11-dione, 1,2,6,7,8,9-hexahydro-1-methyl-6-methylene-, (1R)-

Biological Activity

[Description]:

Methylenedihydrotanshinquinone is a natural product that can be isolated from the dried root of S. miltiorrhiza. Methylenedihydrotanshinquinone has anti-inflammatory effect by inhibiting expression of TNF-α, IL-1β, and IL-8[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Xiangui Mei, et al. Simultaneous qualitative and quantitative determination of 17 bioactive components in the fibrous roots of Salvia miltiorrhiza Bunge by a combinatorial Ultra performance liquid chromatography- Ultraviolet characteristic spectra analysis. Journal of Applied Research on Medicinal and Aromatic Plants. Volume 20, February 2021, 100291.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
483.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆O₃

[ Molecular Weight ]:
280.318

[ Flash Point ]:
216.6±28.8 °C

[ Exact Mass ]:
280.109955

[ LogP ]:
3.90

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.626

Related Compounds

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